Pavel Majer Selected Research

3-(1-carboxy-4-mercaptobutoxy)benzoic acid

5/2006

Structural optimization of thiol-based inhibitors of glutamate carboxypeptidase II by modification of the P1' side chain.

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Pavel Majer Research Topics

Disease

12	Neoplasms (Cancer) 11/2021 - 10/2005
6	Neuralgia (Stump Neuralgia) 01/2017 - 05/2003
5	Prostatic Neoplasms (Prostate Cancer) 05/2015 - 07/2004
2	Infections 01/2022 - 12/2016
2	Nervous System Diseases (Neurological Disorders) 01/2022 - 01/2016
2	Human Influenza (Influenza) 07/2021 - 12/2020
2	Neoplasm Metastasis (Metastasis) 01/2020 - 10/2005
2	Mental Disorders (Mental Disorder) 10/2019 - 10/2017
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 03/2006 - 08/2003
1	Virus Diseases (Viral Diseases) 01/2022
1	Opportunistic Infections (Opportunistic Infection) 01/2021
1	Cryptococcosis 01/2021
1	Neurofibrosarcoma (MPNST) 01/2020
1	Neurofibromatosis 1 (Neurofibromatosis Type I) 01/2020
1	Sarcoma (Soft Tissue Sarcoma) 01/2020
1	Lymphoma (Lymphomas) 11/2019
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 10/2019
1	Anhedonia 01/2019
1	Malaria 12/2017
1	Parkinson Disease (Parkinson's Disease) 12/2017
1	Neurocognitive Disorders (Clerambault Syndrome) 01/2017
1	Glioblastoma (Glioblastoma Multiforme) 09/2016
1	Melanoma (Melanoma, Malignant) 01/2016
1	Hyperalgesia 05/2006
1	Stroke (Strokes) 03/2006
1	Schistosomiasis (Bilharziasis) 04/2005

Drug/Important Bio-Agent (IBA)

9	Glutamate Carboxypeptidase II (N-Acetylaspartylglutamate Peptidase)IBA 01/2022 - 08/2003
8	ProdrugsIBA 01/2022 - 09/2016
6	Glutamine (L-Glutamine)FDA Link 01/2021 - 09/2016
4	Pharmaceutical PreparationsIBA 01/2022 - 03/2006
4	DiazooxonorleucineIBA 11/2019 - 09/2016
4	AntigensIBA 01/2017 - 07/2004
3	Peptide Hydrolases (Proteases)FDA Link 01/2020 - 04/2005
3	Glutamic Acid (Glutamate)FDA Link 01/2017 - 08/2003
2	LuteolinIBA 07/2021 - 12/2020
2	EndonucleasesIBA 07/2021 - 12/2020
2	purineIBA 01/2021 - 01/2020
2	Biological ProductsIBA 12/2020 - 01/2017
2	Analgesics (Analgesic Drugs)IBA 01/2017 - 01/2016
2	EnzymesIBA 12/2016 - 03/2006
1	Antiviral Agents (Antivirals)IBA 01/2022
1	Atrial Natriuretic Factor (ANF)IBA 01/2022
1	PeptidomimeticsIBA 11/2021
1	Proteins (Proteins, Gene)FDA Link 11/2021
1	baloxavirIBA 07/2021
1	Protease Inhibitors (Protease Inhibitor)IBA 01/2021
1	phosphoribosyl-N-formylglycineamideIBA 01/2021
1	FlavonoidsIBA 12/2020
1	Free RadicalsIBA 12/2020
1	RNA-Dependent RNA Polymerase (RNA Dependent RNA Polymerase)IBA 12/2020
1	JHU395IBA 01/2020
1	CarbonIBA 01/2020
1	Cathepsin DIBA 01/2020
1	IsotopesIBA 01/2020
1	KynurenineIBA 01/2020
1	NitrogenIBA 01/2020
1	Pepsin A (Pepsin)IBA 01/2020
1	Carboxylesterase (Hydrolase S)IBA 11/2019
1	Lysine (L-Lysine)FDA Link 11/2019
1	AcidsIBA 10/2019
1	GlutaminaseIBA 01/2019
1	2-(phosphonomethyl)pentanedioic acidIBA 10/2017
1	Carbonic Anhydrase IXIBA 01/2017
1	alkoxyl radicalIBA 01/2017
1	EstersIBA 01/2017
1	CalciumIBA 01/2016
1	glutamate carboxypeptidaseIBA 05/2015
1	3-(1-carboxy-4-mercaptobutoxy)benzoic acidIBA 05/2006
1	Benzoic Acid (Potassium Benzoate)FDA Link 05/2006
1	Capsules (Microcapsules)IBA 10/2005
1	CopperIBA 08/2003
1	Superoxide DismutaseIBA 08/2003
1	ZincIBA 08/2003
1	2-(3-mercaptopropyl)pentanedioic acidIBA 05/2003
1	Sulfhydryl Compounds (Thiols)IBA 05/2003

Therapy/Procedure

5	Therapeutics 07/2021 - 04/2005
3	Oral Administration 01/2014 - 05/2003
1	Immunotherapy 01/2020